Patent · US Expired

Method of inhibiting secretion of inflammatory cytokines

US5545623A · kind A · utility

69Cited by
1References
16Claims
0Family size

Assignees

Inventor

Key dates

Filing dateJun 7, 1995
Grant dateAug 13, 1996
Priority date
Expiry dateJun 7, 2015

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K31/7048
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention discloses a method of inhibiting secretion of inflammatory cytokines in a host which includes administering one or more digitalis compounds in an amount effective for inhibiting secretion of an inflammatory cytokine to the host in need of inhibition of secretion of the inflammatory cytokine. The invention also discloses a method of treating diseases caused by abnormal formation or abnormal secretion of inflammatory cytokines. The invention is useful in the treatment of various diseases ascribed to abnormal secretion/formation of IL=6, IL-8, MCAF, G-CSF and/or GM-CSF.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.