Aryl and heteroaryl macrolides having immunosuppressive activity
US5545734A · kind A · utility
3Cited by
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9Claims
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Key dates
| Filing date | Oct 25, 1994 |
| Grant date | Aug 13, 1996 |
| Priority date | — |
| Expiry date | Oct 25, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Aryl and heteroaryl macrolides of the general structural Formula I: ##STR1## have been prepared from suitable precursors by olefination at C-27. These macrolide immunosuppressants are useful in a mammalian host for the treatment of autoimmune diseases, infectious diseases, the prevention of rejection of foreign organ transplants and/or related afflictions, diseases, and illnesses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.