Production of antibodies from transgenic animals
US5545807A · kind A · utility
1,478Cited by
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5Claims
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Key dates
| Filing date | Aug 5, 1994 |
| Grant date | Aug 13, 1996 |
| Priority date | — |
| Expiry date | Aug 5, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Chimaeric or wholly foreign immunoglobulin is obtained from cells or body fluid of a transgenic animal which has had inserted into its germline genetic material that encodes for at least part of an immunoglobulin, of foreign origin or that can rearrange to encode a repertoire of immunoglobulins, i.e. derived from a different animal source. For example, wholly human immunoglobulins may be produced from a transgenic mouse, possibly in response to an immunogen subsequently introduced to the mouse.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.