Preparation and use of novel injectable RES avoiding inorganic particles for medical application
US5547682A · kind A · utility
22Cited by
42References
13Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 20, 1994 |
| Grant date | Aug 20, 1996 |
| Priority date | — |
| Expiry date | Jul 20, 2014 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2446/90
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel N-RES agents for use in vitro and in vivo medical and biological applications, such as, for example MRI and/or intravenous administration of pharmaceutical agents are described. The novel N-RES agents are prepared by coating inorganic core particles with a poly(acrylic acid)--poly(alkylene ether) graft copolymer. The resulting polymer-coated inorganic particle cores are useful as imaging agents, therapeutic agents or carriers having increased circulation time due to decrease uptake or recognition by the RES.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.