Method and procedure for preparing red blood fractions
US5550060A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 3, 1994 |
| Grant date | Aug 27, 1996 |
| Priority date | — |
| Expiry date | May 3, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/115831
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and apparatus for separating red blood cells by density are described. Older red blood cells are more dense than younger ones. Certain changes in the physiology are recorded in changes in hemoglobin or the red blood cells. By assaying different aged red blood cells, one can determine the historical physiological changes over a period of many weeks. Improved separation of red blood cells is accomplished by using rigid capillary tubes having an inner surface which augments the density equilibrium of red blood cells and/or incrementally increasing the centrifugation forces, as well as by chemically treating red blood cells to improve their deformability.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.