Method for reducing filtrate waste in a manufacturing process of a pharmaceutical product containing benzalkonium chloride
US5550163A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 3, 1994 |
| Grant date | Aug 27, 1996 |
| Priority date | — |
| Expiry date | Aug 3, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/0048
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for reducing filtrate waste in a manufacturing process of a pharmaceutical product containing benzalkonium chloride as a preservative generally includes the steps of mixing the non-benzalkonium chloride components with benzalkonium chloride to formulate the product and thereafter sterilizing the product by passing same through a microfiltration membrane. In processes in which the product has a time dependent benzalkonium chloride content due to benzalkonium chloride adsorption on a microfiltration membrane, an amount of benzalkonium chloride wasted can be reduced by maintaining a selected temperature of the microfiltration membrane and the product therein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.