Bisarylcarbinol derivatives as inhibitors of leukotriene biosynthesis
US5552437A · kind A · utility
7Cited by
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9Claims
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Key dates
| Filing date | Oct 27, 1994 |
| Grant date | Sep 3, 1996 |
| Priority date | — |
| Expiry date | Oct 27, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds having the Formula I: EQU R.sup.1 R.sup.2 C(OR.sup.3)--Ar.sup.1 --X--Ar.sup.2 --Ar.sup.3I re inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection and in preventing the formation of atherosclerotic plaques.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.