5-pyrrolyl-6-halogeno-2-pyridylmethylsulfinyl benzimidazole derivatives
US5554631A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 21, 1995 |
| Grant date | Sep 10, 1996 |
| Priority date | — |
| Expiry date | Mar 21, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P1/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to a novel compound 5-pyrrolyl-6-halogeno-2-pyridylmethylsulfinylbenzimidazole derivative having the following formula (I): ##STR1## or a pharmaceutically acceptable salt thereof, in which X represents S, SO or SO.sub.2, PA0 Y represents halogen, PA0 R.sub.1 and R.sub.2 independently from each other represent hydrogen or methyl, PA0 R.sub.3 represents hydrogen, C.sub.1 -C.sub.8 alkyl, --SR.sub.6, --N(R.sub.7).sub.2, or a group of formula --OR.sub.6 or --O(CH.sub.2).sub.m --Z, wherein PA0 R.sub.6 represents C.sub.1 -C.sub.4 alkyl, C.sub.2 -C.sub.4 alkenyl, C.sub.3 -C.sub.10 cycloalkyl optionally substituted with C.sub.1 -C.sub.4 alkyl, C.sub.2 -C.sub.5 fluoroalkyl, phenyl optionally substituted with C.sub.1 -C.sub.4 alkyl or benzyl optionally substituted with C.sub.1 -C.sub.4 alkyl, PA0 R.sub.7 represents hydrogen or C.sub.1 -C.sub.5 alkyl, PA0 Z represents a group of formula --O(CH.sub.2).sub.q --R.sub.9 wherein PA0 q denotes an integer of 1 to 3, and R.sub.9 represents hydrogen, PA0 m represents an integer of 2 to 10, and
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.