Quinazolinone derivatives possessing calcium uptake inhibiting activity
US5556860A · kind A · utility
10Cited by
10References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 26, 1994 |
| Grant date | Sep 17, 1996 |
| Priority date | — |
| Expiry date | May 26, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D495/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention is to provide quinazolinone derivatives, and their acid salts and quaternary ammonium salts, having an effect of preventing or treating diseases caused by calcium ion overload in cells, such as ischemic heart disease, ischemic cerebral disease and ischemic renal disease, and their usage. The quinazolinone derivatives are represented by the formula: ##STR1## typically, T represents an oxygen atom; Y represents a phenyl or cyclohexyl group; R.sup.1 represents a hydrogen or chlorine atom; R.sup.2 represents a hydrogen atom; ring W represents a benzene or pyridine ring; Z represents a group of the formula: ##STR2##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.