Taxoids, their preparation and the pharmaceutical compositions which contain them
US5556877A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 2, 1994 |
| Grant date | Sep 17, 1996 |
| Priority date | — |
| Expiry date | Mar 2, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to taxoids of general formula (I), their preparation and the pharmaceutical compositions which contain them. The products of general formula (I) have notable antitumoral properties. In the general formula (I), PA0 Ar represents an aryl radical, PA0 R represents a hydrogen atom or an acetyl or alkoxyacetyl radical, PA0 R.sub.1 represents a benzoyl radical or a radical R.sub.2 --O--CO-- in which R.sub.2 represents an alkyl, alkenyl, cycloalkyl, cycloalkenyl, bicycloalkyl, phenyl or heterocyclyl radical, and PA0 R.sub.3 represents an alkyl, alkenyl, cycloalkyl, cycloalkenyl, bicycloalkyl, optionally substituted aryl (with the exception of unsubstituted phenyl) or heterocyclyl radical. ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.