CAP-phenanthroline conjugate for DNA cleavage
US5556949A · kind A · utility
1Cited by
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10Claims
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Key dates
| Filing date | Oct 11, 1994 |
| Grant date | Sep 17, 1996 |
| Priority date | — |
| Expiry date | Oct 11, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/825
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A class of site-specific DNA cleavage agents comprising a sequence-specific DNA binding protein and a nucleolytic moiety attached thereto at an amino acid that is close to DNA in the specific protein-DNA complex, but that is not close to DNA in the non-specific protein DNA complex. These site-specific DNA cleavage agents cleave DNA at specific DNA recognition sites and have little or no non-specific DNA cleavage activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.