Process for preparing glyoxylic acid/dialkyl aminomethylphosphonate mixtures
US5559020A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 8, 1995 |
| Grant date | Sep 24, 1996 |
| Priority date | — |
| Expiry date | Feb 8, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12P7/40
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The invention provides a process for producing mixtures of glyoxylate and a dialkyl aminomethylphosphonate and the subsequent production of N-(phosphonomethyl)glycine, also known as glyphosate. The process comprises preparing in situ a mixture of glyoxylate and a dialkyl aminomethylphosphonate (DEAMPA) by enzymatically reacting glycolic acid (glycolate) and oxygen in an aqueous solution in the presence of a dialkyl aminomethylphosphonate and catalysts consisting of glycolate oxidase and catalase. The resulting mixture can be hydrogenated and then subjected to hydrolysis to produce N-(phosphonomethyl)glycine, a post-emergent phytotoxicant and herbicide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.