DNA encoding a novel mammalian transporter homologous to neurotransmitter transporters and uses thereof
US5559021A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 9, 1993 |
| Grant date | Sep 24, 1996 |
| Priority date | — |
| Expiry date | Nov 9, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention provides an isolated nucleic acid molecule encoding a mammalian rB21a transporter, an isolated protein which is a mammalian rB21a transporter, vectors comprising an isolated nucleic acid molecule encoding a mammalian rB21a transporter, mammalian cells comprising such vectors, antibodies directed to the mammalian rB21a transporter, nucleic acid probes useful for detecting a nucleic acid molecule encoding mammalian rB21a transporter, antisense oligonucleotides complementary to any unique sequences of a nucleic acid molecule which encodes a mammalian rB21a transporter, pharmaceutical compounds related to mammalian rB21a transporter, and nonhuman transgenic animals which express DNA encoding a normal or a mutant mammalian rB21a transporter. This invention further provides methods for determining substrate binding, detecting expression, drug screening, and treatments for alleviating abnormalities associated with the mammalian rB21a transporter.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.