Method of inhibiting viral reproduction using non-phospholipid, paucilamellar liposomes
US5561062A · kind A · utility
9Cited by
9References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 24, 1994 |
| Grant date | Oct 1, 1996 |
| Priority date | — |
| Expiry date | Jun 24, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1272
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A new method of inactivating enveloped viruses and preparations useful in accomplishing this inactivation are disclosed. The method is based on the discovery that paucilamellar lipid vesicles, preferably having non-phospholipids as their primary structural material, can fuse with enveloped virus and that the nucleic acid of the virus denatures shortly after the fusion. The method is useful for inactivating viruses such as orthomyxoviruses, paramyxoviruses, coronaviruses, and retroviruses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.