Recombinant human cytomegalovirus containing foreign gene
US5561063A · kind A · utility
18Cited by
1References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 9, 1993 |
| Grant date | Oct 1, 1996 |
| Priority date | — |
| Expiry date | Dec 9, 2013 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2740/16064
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a virus comprising a DNA sequence essential for replication of a human cytomegalovirus and at least one foreign DNA sequence adapted for expression in a host. The foreign DNA sequence may encode a human immunodeficiency virus anti-sense mRNA sequence or an antigenic polypeptide, e.g., a malarial surface antigen. Also provided are therapeutic compositions and vaccines which comprise the novel viruses of the present invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.