17-.alpha.-acyl steroids which inhibit 5-.alpha.-reductase
US5561124A · kind A · utility
0Cited by
4References
18Claims
0Family size
Inventor
Key dates
| Filing date | May 17, 1995 |
| Grant date | Oct 1, 1996 |
| Priority date | — |
| Expiry date | May 17, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J41/0072
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to substituted 17.alpha.-acyl steroidal 5.alpha.-reductase inhibiting compounds. The invention also relates to pharmaceutical compositions containing these compounds and their use for reducing prostate size and treating prostate adenocarcinoma. Further, the invention describes a process for making these compounds by heating the corresponding substituted 17.beta.-acyl steroid in a solvent, such as ethylene glycol or dimethyl sulfoxide (DMSO), in a base, such as sodium or potassium hydroxide.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.