Process for conditioning of water-soluble substances

US5562923A · kind A · utility

Assignee

• ASTRA CO., LTD. · SE

Inventors

• Jan Trofast · Lund, SE
• Eva Trofast · Lund, SE
• Edib Jakupovic · Nykvarn, SE
• Katarina Bystrom · Genarp, SE

Key dates

• Filing date: Jun 7, 1995
• Grant date: Oct 8, 1996
• Expiry date: Jun 7, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A process for providing water-soluble micronized pharmaceutically acceptable inhalable substances, which can be produced, stored and used while maintaining the aerodynamic properties required for inhalation of the pharmaceutically acceptable substances. This process is carried out by the steps of reducing, if necessary, the residual water from the micronized substance by drying at an elevated temperature and/or vacuum; conditioning the dried, micronized pharmaceutically acceptable inhalable substances with a solvent; and eliminating residual solvent by storing under dry conditions as, e.g., in a vacuum or by purging with a dry, inert gas.