Phospholipid derivatives of nucleosides

US5563257A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Harald Zilch · Mannheim, DE
• Herbert Leinert · Heppenheim, DE
• Alfred Mertens · Schriesheim, DE
• Dieter Herrmann · Kirchzarten, DE

Key dates

• Filing date: May 9, 1995
• Grant date: Oct 8, 1996
• Expiry date: May 9, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12P19/28
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Liponucleotides containing an ether linkage in the 2-position and a thioether, sulfoxide, or sulfone linkage in the 3-position. The nucleoside component of said liponucleotide is AZT or 3'-deoxy-3'-fluorothymidine. These compounds exhibit antiviral activity.