N-(2-sulfatoethyl)piperazine sulfate and its preparation

US5563271A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Michael Meier · Frankfurt am Main, DE
• Heinz-Georg Kautz · Nierstein, DE
• Andreas Schrell · Hofheim, DE

Key dates

• Filing date: Mar 15, 1995
• Grant date: Oct 8, 1996
• Expiry date: Mar 15, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D295/088
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Preparation of N-(2-sulfatoethyl)piperazine sulfate by reacting N-(2-hydroxyethyl)piperazine in a mixture of high- or relatively high-percentage sulfuric acid and oleum or chlorosulfonic acid at temperatures of about 80.degree. C. to about 250.degree. C., introducing the sulfation mixture formed into a water-miscible aliphatic alcohol and isolating the N-(2-sulfatoethyl)piperazine sulfate formed.