Room temperature stable reagent semi-spheres
US5565318A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 2, 1994 |
| Grant date | Oct 15, 1996 |
| Priority date | — |
| Expiry date | Sep 2, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T436/107497
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A reagent semi-sphere is disclosed comprising at least one biological reagent and a glass forming filler material in a concentration sufficient to facilitate formation of a glassy, porous composition, wherein the reagent semi-sphere is room temperature stable, water soluble, and has a T.sub.g above room temperature. A method is provided for making the reagent semi-sphere comprising providing an aqueous solution of a buffered biological reagent; mixing a glass forming filler material with the buffered reagent solution to form an emulsion wherein the concentration of the filler material is sufficient to facilitate formation of a glassy, porous composition having a predetermined semi-spherical shape; dispensing the emulsion in the form of substantially uniform droplets; collecting the droplets on an inert medium to form semi-spheres; and vacuum drying the droplets, under conditions suitable for maintaining the predetermined semi-spherical shape, to form the reagent semi-sphere; wherein the reagent semi-sphere is room temperature stable, water soluble, and has a T.sub.g above room temperature.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.