Cytochrome oxidase mutations aiding diagnosis of sporadic alzheimer's disease
US5565323A · kind A · utility
37Cited by
0References
16Claims
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Assignee
Inventors
Key dates
| Filing date | Mar 30, 1994 |
| Grant date | Oct 15, 1996 |
| Priority date | — |
| Expiry date | Mar 30, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to genetic mutations in mitochondrial cytochrome oxidase genes that segregate with Alzheimer's disease (AD). The invention provides methods for detecting such mutations, as a diagnostic for Alzheimer's Disease, either before or after the onset clinical symptoms. The invention further provides treatment of cytochrome oxidase dysfunction.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.