Methods of using lysophosphatidic acid for treating hyperproliferative conditions
US5565439A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 4, 1994 |
| Grant date | Oct 15, 1996 |
| Priority date | — |
| Expiry date | Nov 4, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/665
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The subject invention involves a method for treating hyperproliferative conditions in mammalian epithelial cells comprising administering to the mammal a composition containing a safe and effective amount of a lysophosphatidic acid compound or derivative having the structure ##STR1## or a cyclic derivative thereof having the structure ##STR2## or a pharmaceutically acceptable salt thereof, wherein: a) --Y-- is --0-- or --CH.sub.2 --; PA1 b) --Z is --XH, --H or halo; PA1 c) each --X-- is independently --0-- or --S--; and PA1 d) --R is unsubstituted or substituted, saturated or unsaturated, straight or branched chain alkyl having from 11 to about 23 carbon atoms.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.