Biphenyl compounds useful or endothelin antagonists
US5565485A · kind A · utility
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23Claims
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Key dates
| Filing date | Aug 22, 1994 |
| Grant date | Oct 15, 1996 |
| Priority date | — |
| Expiry date | Aug 22, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D409/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Phenoxyphenylacetic acids and derivatives of the general structural formula I ##STR1## have endothelin antagonist activity and are useful in treating cardiovascular disorders, such as hypertension, postischemic renal failure, vasospasm, cerebral and cardiac ischemia, myocardial infarction, endotoxic shock, benign prostatic hyperplasia, inflammatory diseases including Raynaud's disease and asthma.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.