Oxalylamino-benzofuran- and benzothienyl-derivatives

US5565488A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Gabriele Braunlich · Wuppertal, DE
• Rüdiger Fischer · Pulheim, DE
• Mazen Es-Sayed · Langenfeld, DE
• Rudolf Hanko · Düsseldorf, DE
• Stephen Tudhope · Windsor, GB
• Graham Sturton · Maidenhead, GB
• Trevor S. Abram · Marlow, GB
• Wendy J. McDonald-Gibson · Wallingford, GB
• Mary F. Fitzgerald · Yarnton, GB

Key dates

• Filing date: May 23, 1995
• Grant date: Oct 15, 1996
• Expiry date: May 23, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The inventive Oxalylamino-benzofuran- and benzothienyl-derivatives are prepared by reacting the appropriate amino substituted benzofuranes and benzothiophenes with oxalic acid derivatives. The inventive compounds are suitable for the prevention and treatment of acute and chronic inflammatory processes, particularly of the airways.