Patent · US Expired

Multisample magnetic separation device

US5567326A · kind A · utility

70Cited by
21References
15Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 19, 1994
Grant dateOct 22, 1996
Priority date
Expiry dateSep 19, 2014

Classification

  • Technology area (CPC G)Physics
  • CPC primaryG01N35/0098
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Apparatus and methods for separating magnetically responsive particles from a nonmagnetic test medium in which the magnetically responsive particles are suspended. The separator comprises a container comprising, e.g., plurality of multiwell chambers, which hold the nonmagnetic test medium, one or more pins disposed substantially within the test medium, an external magnet for producing a magnetic field within the test medium. The external magnet is proximate the pins so as to create magnetic flux lines, magnetizing the pins and creating a magnetic field substantially parallel to the longitudinal axis of the pins thereof in the test medium. According to the method of the invention, the container holding the test medium is positioned in the separator, producing a magnetic field operative to cause the magnetically responsive particles to be attracted to and adhere to the pins and which is substantially parallel thereto. The nonmagnetic test medium is separated from the magnetized particles, which may conveniently be washed while adhered to the pins, and subjected to further analysis, preferably while on the pins. The apparatus and method are useful in separating various target substanc…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.