Patent · US Expired

Methods for enhancing vascularization of implant devices

US5569462A · kind A · utility

350Cited by
84References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 31, 1995
Grant dateOct 29, 1996
Priority date
Expiry dateMar 31, 2015

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S623/915
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Methods for enhancing vascular support of cells housed within an implanted apparatus are disclosed. The methods comprise placing a population of therapeutic substance-producing cells into the cell receiving chamber of an immunoisolation apparatus, implanting the apparatus into a patient, and administering an immunomodulatory agent to the patient. The immunomodulatory agent increases the number of close vascular structures in the vicinity of the implanted device, which increases the long term survival of the cell population housed therein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.