Transgenic mice containing a disrupted p53 gene
US5569824A · kind A · utility
19Cited by
3References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 21, 1994 |
| Grant date | Oct 29, 1996 |
| Priority date | — |
| Expiry date | Jul 21, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2267/0331
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A desired non-human animal or an animal cell or human cell which contains a predefined, specific and desired alteration in at least one of its two p53 chromosomal alleles, such that at least one of these alleles contains a mutation which alters the expression of the allele, and the other of the alleles expresses either a normal p53 gene product, or comprises an identical or different p53 mutation.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.