Patent · US Expired

Method for the cell-free synthesis of proteins

US5571690A · kind A · utility

6Cited by
6References
11Claims
0Family size

Assignee

Inventor

Key dates

Filing dateMay 8, 1991
Grant dateNov 5, 1996
Priority date
Expiry dateMay 8, 2011

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12P21/02
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

A method is disclosed for the reliable production of proteins by amplifying, transcribing and translating the gene encoding the protein in an essentially cell-free system (gene amplification with transcription/translation, GATT). In the case of dihydrofolate reductase (DHFR), over 1 billion copies of DHFR are produced per original fol gene.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.