Patent · US Expired

Histidine and homohistidine derivatives as inhibitors of protein farnesyltransferase

US5571792A · kind A · utility

49Cited by
2References
19Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 30, 1994
Grant dateNov 5, 1996
Priority date
Expiry dateJun 30, 2014

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Novel inhibitors of protein farnesyltransferase enzyme are described, as well as methods for the preparation and pharmaceutical compositions of the same, which are useful in controlling tissue proliferative diseases, including cancer and restenosis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.