Patent · US Expired

Synergistic antiviral nucleoside combinations

US5571798A · kind A · utility

5Cited by

11References

3Claims

0Family size

Inventors

Johan Harmenberg · Stockholm, SE
Britta Wahren · Stockholm, SE
Bo F. Oberg · Uppsala, SE

Key dates

Filing date	Dec 9, 1994
Grant date	Nov 5, 1996
Priority date	—
Expiry date	Dec 9, 2014

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P43/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

An antiviral composition comprising in combination an effective antiviral amount of 3'-fluoro-2',3'-dideoxy nucleoside compound I of the formula ##STR1## wherein B is adenine, thymine, guanine, cytosine, inosine, uracil, 5-ethyluracil, 2,6-diaminopurine; and an effective antiviral amount of 2',3'-dideoxy nucleoside compound II of the formula ##STR2## wherein X is N.sub.3 or H or together with Y forms an additional carbon-carbon bond, Y and Z are independently H, OH or F, and B is adenine, thymine, guanine, cytosine, inosine, uracil, 5-ethyluracil, 2,6-diaminopurine, and a physiologically acceptable carrier.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.