Pyrimidines

US5571816A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Klaus-Dieter Kampe · Bad Soden am Taunus, DE
• Ernold Granzer · Kelkheim, DE
• Michael Leineweber · Frankfurt am Main, DE
• Gerhard Rackur · Idstein, DE
• Hans G. B oger · Hofheim, DE

Key dates

• Filing date: Aug 16, 1995
• Grant date: Nov 5, 1996
• Expiry date: Aug 16, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D233/38
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of the formula I ##STR1## in which R.sup.1 to R.sup.6 have the stated meanings, and the readily water-soluble salts of these compounds, and a process for the preparation thereof are described. The compounds are suitable for the treatment of lipid metabolism disorders which are beneficially influenced by a stimulation of the hepatic LDL receptor. Also described are compounds of the formula II ##STR2## and the salts thereof.