Viral attachment inhibitors
US5571836A · kind A · utility
1Cited by
0References
19Claims
0Family size
Inventors
Key dates
| Filing date | May 9, 1995 |
| Grant date | Nov 5, 1996 |
| Priority date | — |
| Expiry date | May 9, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/70
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Viral attachment to target cells is inhibited by novel neuraminic acid compounds of the formula: ##STR1## wherein R.sup.1 is selected from the group consisting of hydrogen and acetyl; R.sup.2 is selected from the group consisting of hydrogen and methyl; and Y is selected from the group consisting of: ##STR2## The novel compounds bind virus particles and are substantially uncleaved by neuraminidase. Coupling of the novel compounds to a polymer further inhibits viral attachment.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.