Method for producing 2-methylspiro(1,3-oxathiolane-5,3')quinuclidine
US5571918A · kind A · utility
4Cited by
1References
16Claims
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Key dates
| Filing date | May 11, 1995 |
| Grant date | Nov 5, 1996 |
| Priority date | — |
| Expiry date | May 11, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for producing 2-methylspiro(1,3-oxathiolane-5,3')quinuclidine, which comprises reacting 3-hydroxy-3-mercaptomethylquinuclidine or a salt thereof and a carbonyl compound in the presence of a catalyst made of at least one member selected from the group consisting of tin halides, oxyacids of phosphorus, phosphorus oxyhalides and organic sulfonic acids, to produce cis-form 2-methylspiro(1,3-oxathiolane-5,3')quinuclidine or a salt thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.