Methods and materials for detecting autoimmune antibodies
US5573911A · kind A · utility
2Cited by
6References
22Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 3, 1994 |
| Grant date | Nov 12, 1996 |
| Priority date | — |
| Expiry date | Oct 3, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/809
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The subject invention pertains to a method of binding proteins and double-stranded DNA to the same membrane matrix. The DNA bound to the membrane matrix remains in double-stranded form. The subject invention further concerns an assay procedure for detecting antibodies, such as autoimmune antibodies, in a biological sample that are immunoreactive with the proteins and double-stranded DNA attached to a membrane matrix. The subject invention provides a single assay system that allows for the determination of antinuclear antibody specificities which can be used to aid in the diagnosis and monitoring of autoimmune diseases.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.