Inhibitors of prenyl-protein transferases
US5574025A · kind A · utility
20Cited by
12References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 26, 1994 |
| Grant date | Nov 12, 1996 |
| Priority date | — |
| Expiry date | Oct 26, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/3826
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The compounds disclosed inhibit the prenylation of several proteins. These compounds are potent inhibitors of famesyl-protein transferase and geranylgeranyl-protein transferase. Further contained in this invention are chemotherapeutic compositions containing these prenyl-transferase inhibitors and methods for their production.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.