Piperazine carboxamides

US5574031A · kind A · utility

Assignee

• Pharmacia Corporation · SE

Inventors

• Lisbeth Abramo · Bjärred, SE
• Torbj orn Lundstedt · Hultsfred, SE
• Curt Nordvi · Bissenkamp, SE
• Knut G. Olsson · Malmö, SE
• Martin Brodszki · Malmö, SE

Key dates

• Filing date: Jan 31, 1995
• Grant date: Nov 12, 1996
• Expiry date: Jan 31, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/74
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of general formula (I) are useful for treating mental disorders, wherein R.sub.1 and R.sub.2 are the same or different and selected from hydrogen or lower alkyl; Ar are the same or different and selected from pyridyl and phenyl groups, n is 1 or 2, X is nitrogen or methine. When X is nitrogen, Y is methylene. When X is methine, Y is selected from nitrogen or oxygen. A is selected from carboxylic derivatives. The pharmacologically active salts of formula (I) are also embraced. ##STR1##