Antiproliferative compounds having nitrogen-containing tricyclic ring systems and phenyl substituents
US5574039A · kind A · utility
1Cited by
11References
20Claims
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Key dates
| Filing date | Sep 22, 1994 |
| Grant date | Nov 12, 1996 |
| Priority date | — |
| Expiry date | Sep 22, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/92
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to TS-inhibiting compounds of the formula ##STR1## where W is an alkylene group; D is a structure having two rings that are unsubstituted or substituted, where (i) one ring is a phenyl ring and (ii) the other ring is a phenyl ring or a 6-membered heterocyclic ring; R is a hydrogen atom or an alkyl group; and X and Y together form ##STR2## and to salts of these compounds. The moiety W can be CH.sub.2, and D can be a phenyl ring bridged through a sulfonyl group to another ring.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.