Pyrimidine compounds and methods of use to derivatize neighboring lysine residues in proteins under physiologic conditions
US5574040A · kind A · utility
7Cited by
5References
12Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 6, 1995 |
| Grant date | Nov 12, 1996 |
| Priority date | — |
| Expiry date | Jan 6, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D251/48
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound according to the formula: ##STR1## wherein A=CH.sub.3 or CH.sub.2 CH.sub.3 and ##STR2## wherein X=NH.sub.2, CH.sub.2 or CH.sub.2 CH.sub.3 ; X'=CH.sub.3 or CH.sub.2 CH.sub.3 ; Y=NH.sub.2, NHCH.sub.3, N(CH.sub.3).sub.2 ; and Z=H, CH.sub.3 or CH.sub.2 CH.sub.3 ; or ##STR3## wherein Y' and Z', indepedently, = H, NH.sub.2, NHCH.sub.3, N(CH.sub.3).sub.2 or N.sup.+ (CH.sub.3).sub.3 ; and salts thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.