Inhibitors of farnesyl-protein transferase
US5576313A · kind A · utility
25Cited by
7References
11Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 29, 1994 |
| Grant date | Nov 19, 1996 |
| Priority date | — |
| Expiry date | Aug 29, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/54
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to compounds which inhibit farnesyl-protein transferase (FTase) and the farnesylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting farnesyl-protein transferase and treatment of cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.