Dihydropyridinecarboxylic acid anhydrides
US5576439A · kind A · utility
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4References
11Claims
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Assignee
Inventor
Key dates
| Filing date | Oct 28, 1994 |
| Grant date | Nov 19, 1996 |
| Priority date | — |
| Expiry date | Oct 28, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D211/90
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to the compounds of formula I ##STR1## wherein R is lower alkyl or hydrogen; R.sub.1 is hydrogen, lower alkyl or aryl-lower alkyl; R.sub.2 is hydrogen, nitro, cyano trifluoromethyl, halo, lower alkoxy, lower alkyl, lower alkoxycarbonyl, aminocarbonyl or mono- or di-lower alkylaminocarbonyl, amino or mono- or di-lower alkylamino; and pharmaceutically acceptable salts thereof when R.sub.1 is hydrogen; which are useful as endothelin antagonists.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.