NF2 isoforms
US5578462A · kind A · utility
4Cited by
0References
16Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 10, 1994 |
| Grant date | Nov 26, 1996 |
| Priority date | — |
| Expiry date | Jan 10, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel human and mouse NF2 transcript isoforms and proteins encoded thereby, are disclosed. The isoforms are found in a variety of tissue and tumor types and represent differential processing of genomic DNA sequences, at the level of transcription, resulting in variant proteins. The isoforms provide useful tools for the analysis of the normal function of tumor suppressor factors, such as the merlin protein, and also provide useful markers for the detection of NF2 disease.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.