Hybridoma and monoclonal antibody 9H10-A4 specific to an antigen of LNCaP cells
US5578484A · kind A · utility
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Key dates
| Filing date | Sep 16, 1994 |
| Grant date | Nov 26, 1996 |
| Priority date | — |
| Expiry date | Sep 16, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Monoclonal antibodies, specifically 9H10-A4 monoclonal antibodies, specific to an epitope present on the surface of LNCaP cells, are produced by hybridoma cell line 9H10-A4 formed by fusing mouse lymphocytes and mouse myeloma cells. 9H10-A4 monoclonal antibodies are useful to positively identify LNCaP cells and distinguish them from other cultured cells, and as a reliable control in competitive binding studies for detection of circulating antigens associated with prostate carcinoma.
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