Viral integrase inhibiting peptides
US5578573A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 20, 1995 |
| Grant date | Nov 26, 1996 |
| Priority date | — |
| Expiry date | Jan 20, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K7/06
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides viral integrase inhibiting peptides having the general structure, ##STR1## where Xaa is an amino acid or an amino acid analog, the stereochemistry of the amino acids or amino acid analogs can be D-amino acids or L-amino acids and the amino and carboxy termini of the peptide can be modified. The invention also provides viral inhibiting peptides having essentially the amino acid sequence, ##STR2## The invention also provides a pharmaceutical composition comprising a viral integrase inhibiting peptide and methods of using a viral integrase inhibiting peptide in vitro or in vivo to reduce or inhibit viral integrase activity in a cell and the infectivity of a virus.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.