Patent · US Expired

1H-indole-3-acetic acid hydrazide sPLA.sub.2 inhibitors

US5578634A · kind A · utility

23Cited by
7References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 12, 1995
Grant dateNov 26, 1996
Priority date
Expiry dateMay 12, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D401/12
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A class of novel 1H-indole-3-acetic acid hydrazides is disclosed together with the use of such indole compounds for inhibiting sPLA.sub.2 mediated release of fatty acids (e.g., arachidonic acid) for treatment of conditions such as septic shock.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.