Substantially pure receptor like TFG-.beta.1 binding molecules
US5578703A · kind A · utility
14Cited by
2References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 22, 1994 |
| Grant date | Nov 26, 1996 |
| Priority date | — |
| Expiry date | Apr 22, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention relates to a family of substantially pure, receptor like TGF-.beta.1 binding glycoproteins. These molecules are characterized by molecular masses of 160 kd, 70-80 kd, and 30-40 kd as determined by SDS-PAGE, and the ability to bind the TGF-.beta.1 molecule. This family of molecules is useful in identifying and/or quantifying TGF-.beta.1 in a sample, as well as inhibiting its effect on cells. Also described are nucleic acid sequences which code for the protein monomer making up the molecules.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.