Macromolecular microparticles and methods of production
US5578709A · kind A · utility
163Cited by
17References
18Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Mar 4, 1994 |
| Grant date | Nov 26, 1996 |
| Priority date | — |
| Expiry date | Mar 4, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/812
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A macromolecular microparticle composition formed by dehydrating an aqueous macromolecule solution and crosslinking the dehydrated macromolecules with a crosslinking agent while in a liquid phase or with heat. Preferably, the dehydrating agent is a polymer mixture of polyvinylpyrrolidone and polyethylene glycol, the crosslinking reagent is glutaraldehyde, and the macromolecule is a protein, most preferably an immunoglobulin. Methods of use for research, diagnostics and therapeutics are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.