Hybrid plasminogen activator
US5580559A · kind A · utility
2Cited by
2References
5Claims
0Family size
Assignee
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Key dates
| Filing date | Sep 23, 1994 |
| Grant date | Dec 3, 1996 |
| Priority date | — |
| Expiry date | Sep 23, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/702
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Novel single-chain hybrid plasminogen activators having an amino acid sequence composed of at least two subsequences corresponding in amino acid identity and number to subsequences of human t-PA and of human u-PA, and mutants thereof in which at least one of the N-glycosylation sites is modified such that glycosylation cannot take place at these sites exhibit valuable pharmacological properties. The hybrid plasminogen activators are produced by recombinant DNA technology.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.