Patent · US Expired

Method of treating the symptoms of human rhinovirus infection

US5580577A · kind A · utility

3Cited by
24References
2Claims
0Family size

Inventors

Key dates

Filing dateOct 17, 1995
Grant dateDec 3, 1996
Priority date
Expiry dateOct 17, 2015

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K31/198
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A method of treating viral infection comprises the step of administering to a patient harboring a disease-inducing virus other than HIV-1, the virus being one for which an intracellular thiol deficit causes or exacerbates expression of viral genetic information by transcription, translation or viral replication, such as human rhinovirus, an amount effective to inhibit transcriptional or translational expression of genetic information or replication of the virus, of an N-(C.sub.1-4)-acylcysteine, such as N-acetyl cysteine, or a pharmaceutically acceptable salt thereof. Prevention of disease symptoms and reduction of their severity results from the foregoing treatment. Combination of N-(C.sub.1-4)-acylcysteine or its salt with another antiviral drug or drug for alleviating symptoms of viral infection provides additional therapeutic benefits.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.