Patent · US Expired

Nitroxyalkylamide derivatives

US5580893A · kind A · utility

2Cited by
4References
80Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 25, 1994
Grant dateDec 3, 1996
Priority date
Expiry dateJul 25, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D333/38
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Nitroxyalkylamide compounds having the formula: R.sup.1 --(A).sub.n --CONH--B'--ONO.sub.2 wherein R.sup.1 is an optionally substituted furyl, furyloxy, thienyl, thienyloxy, isoxazolyl, phenoxy, phenylthio or 1,4-dibenzodioxanyl, A is a C.sub.1 -C.sub.4 alkylene group; B' is a C.sub.1 -C.sub.4 alkylene group; and n is 0 or 1. The compounds of the present invention have a desirable vasodilator action for collateral vessels and an anti-anginal action, and are useful as therapeutic agents for treating angina pectoris.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.