Process for preparing optically active nucleosides from chiral cyclobutanones
US5580973A · kind A · utility
1Cited by
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21Claims
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Inventors
Key dates
| Filing date | Jan 7, 1994 |
| Grant date | Dec 3, 1996 |
| Priority date | — |
| Expiry date | Jan 7, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H19/16
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process is disclosed for the preparation of optically active purine nucleosides, particularly nucleosides of formulae 1 and 2, nucleoside analogs and optically active intermediates of formula 3 which may be used in the preparation of nucleosides of the formula 4 as well as a purine nucleosides and nucleoside analogs. ##STR1## The process is directed to the preparation of such compounds, including novel such compounds in their respective .alpha.- and .beta.-anomeric forms, and the enantiomeric forms of these compounds. These compounds show various levels of anti-viral and/or anti-cancer activity.
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